Vesicular carriers containing phenylethyl resorcinol for topical delivery system; liposomes, transfersomes and invasomes
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چکیده
منابع مشابه
Ethosomes of Phenylethyl Resorcinol as Vesicular Delivery System for Skin Lightening Applications
Ethosome formulations containing phenylethyl resorcinol (PR) were developed. The formulation was produced from 0.5% w/v PR, 0.5% w/v cholesterol from lanolin, 3% w/v L-α-phosphatidylcholine from soybean, 30% v/v absolute ethanol, and water up to 100% v/v. It was characterized by a vesicular size of 389 nm, low polydispersity index of 0.266, zeta potential of -34.19 ± 0.44 mV, high PR entrapment...
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Invasomes are the liposomal vesicles embodying small amounts of ethanol and terpenes or terpene mixtures, which act as potential carriers with increased skin penetration. Invasomes have higher penetration rate through the skin as compared to liposomes and ethosomes. Invasomes provide a number of advantages including improving the drug’s efficacy, enhancing patient compliance and comfort. This a...
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Delivery of drug through Transdermal route represents a most convenient and novel approach. Transfersomes were found to be more effective as they render controlled release of drug due to depot formation in skin and were more effective in transdermal delivery. Transfersomes are applied to the skin and permeate through the stratum corneum lipid lamellar regions as a result of the hydration and os...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical Sciences
سال: 2018
ISSN: 1818-0876
DOI: 10.1016/j.ajps.2018.02.004